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3 tips to using Bioidentical Estrogen (Biest) Cream



Estrogens are what make a woman a woman

There are several different types of estrogens. There is estrone, otherwise known as E1. There is estridiol, known as E2. Then there is estriol, known as E3.

Estrone actually becomes the dominant hormone as a woman ages. The reason being is that fat makes estrone, and we all know that Americans usually have way to much of that. Another reason is that estrone is converted into a form of itself that is stored.

Estradiol is the Incredible Hulk when it comes to the estrogens. It is 10 times more potent than estrone and 80 times more potent than estriol. As estradiol becomes deficient, menopause occurs. Once estradiol starts to decrease, aging starts to accelerate. Higher levels of estradiol that are balanced with the other two sex hormones keeps a woman feminine. It makes the hair and skin youthful. It is what makes women soft and curvaceous. Deficient estradiol causes roundness, wrinkles, low energy and loss of that youthful zest. The symptoms that women complain about the most when estadiol becomes deficient are hot flashes and night sweats.

Estriol is the weakest of the three estrogens. It is the estrogen that keeps the vagina youthful. When estriol becomes deficient the vaginal wall becomes thin. This causes pain on intercourse. This epithelial thinning also causes menopausal incontinence-small amounts of urnine will be expelled upon sneezing and coughing . The symptom that women complain about the most when estriol is deficient is vaginal dryness.

Estrogen Dominance

As men and women age the conversion of testosterone and progesterone to estrogens becomes a problem. Estrogen becomes the dominant hormone. Testosterone and progesterone are converted into estrogen by an enzyme in fat cells. Estrogen is a fat storing hormone. Progesterone and testosterone are fat burning hormones. The more dominant estrogen becomes the more fat that is stored. At the same time, there is less and less of the fat burning hormones, testosterone and progesterone. Estrogen, fat storing becomes dominant. Testosterone and progesterone, fat burning becomes subordinant. This imbalance of hormones causes a condition called weight loss resistance. Weight Loss Resistance is defined as the inability to lose weight no matter what you do. You join the gym, cut your calories and you gain two pounds.

How to Dose Bioidentical Estrogens

In the beginning of bioidentical hormone therapy, anti-aging physicians use to prescribe a cream that combined all three estrogens. Once it was discovered that the body had to much estrone, we took the estrone component out of the prescription. The compounded cream that was used in the beginning was called tri-est.

The Mac Protocol believes that the best dosing of bioidentical hormones is to start with very low doses. After a month reevaluate the symptoms. The dosing will stay the same if positive results are occurring. If certain symptoms are unaffected than the dosing will be adjusted for your bio-individuality. We have found that a majority of the low estrogen symptoms are relieved with a fifth of the normal dose used by conventional medicine. We have also found that by using small doses, the body's internal resourcing of hormones are stimulated instead of being shut down.

The Mac Protocol believes that hormone therapy should be the used as a primer. Hormones should be used to start the engine, not as the fuel to keep the the engine running. Once our hormones increase, we become more active. We start doing an old hobby, like gardening. This will increase our hormones naturally. We then start going to the gym, hormones increase even more, then we start riding a bike, more natural hormonal increases, than we start making love more often, even higher hormone levels. 

We recommend to start with a foundation month, a month of introducing low doses. Most patients begin with a dose of 1 mg of biest in a combination of E2 and E3. The percentage is 20% estradiol, (E2), and 80% estriol, (E3). This small dose will usually handle hot flashes, night sweats and vaginal aging.

The cream is to be applied to thin skin. We usually recommend to apply the cream to your inner arms than rotate to inner thighs after a few months than rotate back to the inner arms. Use the creams after bath so the pores are opened and the cream will be easily absorbed. Rub the creams back and forth at least ten times. Do not swim or bathe again for at least two hours after application.

The 3 Secrets to Bioidentical Hormone Estrogen

  1. Use low doses
  2. Start at a combination of 20% E2 and 80% E3
  3. Apply the cream after bath on thin skin

 If you would like more information about The Mac Prototol

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 The Macs

Heathy Aging Consultants


I had a total hysterectomy six months ago my doctor prescribed Premarin for me but I refuse to take it because of the side the present I'm experincing hot flashes and night sweats and taking an over the counter medicine called estroven which is not very helpful as the box states, my question is will Bi est help me since I've had a complete hysterectomy ?
Posted @ Sunday, December 30, 2012 9:55 AM by Pam Miller
bio identicals saved my life! after 2 years of suffering mega hot flashes no sleep falling out hair and 30 lbs weight gain plus complete exhaustion, depression, rapid aging and dry soreness below, I became disabled! GP diagnosed Chronic Fatigue and prescribed anti depressants. what a joke! a hormone specialist put me on Progesterone for a while to deal with estrogen dominance. then we added Testosterone and then Bi est, plus thyroid. I am a NEW WOMAN now, back to work back to gym Ladies, there's no need to suffer, get hormones for quality of life!
Posted @ Thursday, September 12, 2013 6:41 AM by neeters
I am taking 2mg of biest? My doctor wants to increase it to 3. Is that too much? 
Posted @ Thursday, May 01, 2014 8:44 PM by Debbie
no---you can always lower it back to 2. I took 3 mg for 10 weeks but had side effects of tenderness, but I really needed the 3 mg to balance
Posted @ Tuesday, May 13, 2014 4:09 PM by Jane
I just started it 3 days ago and my distended tummy has increased. is it my imagination? CARIE
Posted @ Monday, June 16, 2014 1:15 AM by carole
I have experienced significant belly fat as well as difficulty losing weight even with exceeding and dieting. I am on 1mg of Biest (80/20). Has anyone else experienced this?
Posted @ Wednesday, July 16, 2014 12:18 PM by
Need any advice you can give. Hysterectomy 6 months ago Started estradiol 2 months ago with no relief from being exhausted and no sleep. Need info on bi-est.
Posted @ Tuesday, April 07, 2015 9:47 PM by Debra
Taking biest 0.75mg. I have experienced tummy and thigh fat. Is this too little ?
Posted @ Tuesday, April 14, 2015 12:07 AM by Kathy
Great Tips indeed regarding women issues.
Posted @ Monday, April 27, 2015 7:49 PM by Vagina Tight Cream
I've had a hysterectomy back in 2011.. I have no uterus and my ovaries no longer produces hormones.., I saw my endocrinologist & my Ob Gyn.. Both said to stop taking progesterone since I have no uterus but stay with biest  
cream estradiol cream from bio  
identical.. Can anyone please respond and tell me if I should listen to the both  
doctors .. Or listen to the hormone doctor who prescribed progesterone &  
Posted @ Sunday, May 03, 2015 9:57 AM by Norma
i am using 0.4ml of 1.25mg/ml bi-est cream each night applying to inner labia, but still experiencing vaginal dryness and weight gain should I be using more or less or apply to inner arm or split dose also using 0.6 of progesterone versa 120mg/ml to inner arms at bedtime trying to get balanced for last 5 years since having early hysterectomy in 30's
Posted @ Sunday, June 21, 2015 2:46 PM by Jodie
My prescription bioidentical creme is Estradiol 1/5mg - Progestrone 200mg - Testerone 7.5mg. I only use this creme once a day at night after my shower. Only one pharmacy where I live mix it. I apply it where my ovaries are because where ever I apply it I grow hair. (Should try it on my husbands head, lol) Anyway I can't live without this cream. I call it my miracle. I tried many other products before this and none worked. This cream takes care of it all. No hot flashes, no dryness, and I got my drive back !! The doctor that orginally prescribed it did my bloodwork to see what my levels were for all those hormones and they were at 0. I haven't had them tested for a while, but I want to so I can see if I need to adjust the amounts. It is very expensive. Hope this helps, because it works for me!
Posted @ Friday, July 10, 2015 12:59 AM by Leisa Urse
Nice post.
Posted @ Wednesday, August 05, 2015 2:53 AM by Max
Great to know about this product. It is always a good idea to consult the doctor before using any type of cream or product to heal and cure any type of disease.
Posted @ Wednesday, August 05, 2015 3:56 AM by Daisy Hester
Nice post.Estrogen amount should be normal in women always.
Posted @ Saturday, August 08, 2015 2:09 AM by foot support for plantar fasciitis
Thanks for sharing! Bioidentical Hormones Are Safe for Women Help Relieve Menopause Symptoms.
Posted @ Monday, August 10, 2015 10:49 AM by reese
What is the best dosage of estrogens an progestrons by troche . I'm on 1.8 mg biest troche and 40mg progesterone by troche . My breast are sore and I have weight gain . I workout but isn't helping
Posted @ Monday, August 31, 2015 1:15 PM by Tammy Moore
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